MicroRNAs in Ocular Infection

Lagenidium sp. ocular infection mimicking ocular pythiosis.

This is a report of a Lagenidium sp. in a Thai patient who was diagnosed with severe keratitis that was unresponsive to antibacterial and antifungal drugs. Examination of a corneal biopsy specimen confirmed the presence of aseptate hyphae. The internal transcribed spacer DNA sequence of the strain isolated showed 97% identity with Lagenidium giganteum and other Lagenidium species.

Lagenidium sp . ocular infection mimicking ocular

Usanee Reinprayoon*, Nitipong Permpalung*, Ngamjit Kasetsuwan, Rongpong Plongla, 2 Leonel Mendoza, Ariya Chindamporn 3 Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, 4 Thailand, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand, 5 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, 6 Thailand, De...

MicroRNAs in vitreus humor from patients with ocular diseases

PURPOSE Based on evidence that microRNAs (miRNAs) are found in many biologic fluids (e.g., urine, saliva, pleural fluid), we sought to detect the presence of miRNAs and analyze their profile in vitreous humor (VH) from patients affected by various ocular diseases. METHODS MiRNAs were purified from VH samples taken during vitrectomy, by using the Qiagen miRNeasy Mini Kit. The expression profil...

Ocular Infection Update

Ocular infection and inflammation.

Managing the inflamed or infected eye in the emergency setting presents a diagnostic and therapeutic challenge to the emergency physician; the causes and prognoses range from benign, self-limited illness to organ-threatening pathology. A careful history, with attention to comorbid illnesses and time course, is paramount, as is knowledge of the complete ophthalmologic examination. Much of the or...